Written by OC Wellness Physicians » Updated on: June 17th, 2025
Knee pain is a common ailment that affects millions of Americans each year. Whether caused by arthritis, sports injuries, or age-related wear and tear, finding effective treatment options can be life-changing. Two innovative approaches—Platelet-Rich Plasma (PRP) therapy and Stem Cell Therapy—have gained significant attention as non-surgical alternatives for alleviating knee pain and promoting healing. But how do these treatments compare? Let’s break it down.
PRP therapy involves using the patient’s own blood to stimulate healing. The process starts with drawing a small amount of blood, which is then spun in a centrifuge to concentrate the platelets. These platelets, rich in growth factors, are injected into the injured or painful area of the knee.
Stem cell therapy harnesses the body’s regenerative power to repair damaged tissues. Stem cells, which can develop into various types of cells, are harvested from the patient’s bone marrow or fat tissue. Once prepared, these cells are injected into the knee to encourage tissue repair and reduce inflammation.
Deciding between PRP and stem cell therapy depends on several factors, including:
In the United States, PRP and stem cell therapies are typically considered elective procedures, meaning they are not covered by most insurance plans. However, some clinics offer financing options to make these treatments more affordable.
Final Thoughts
Both PRP and stem cell therapy represent promising advancements in the treatment of knee pain, offering patients alternatives to surgery and long-term medication use. While PRP focuses on accelerating the body’s natural healing process, stem cell therapy dives deeper by regenerating damaged tissues.
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