Chlorpheniramine Maleate Tablet: Uses, Dosage, Side Effects & Precautions

Chlorpheniramine Maleate Tablet is an antihistamine commonly used to relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, and skin rashes. It is widely prescribed for conditions like hay fever, urticaria (hives), and allergic reactions caused by pollen, dust, or pet dander. The medication works by blocking histamine, a chemical in the body responsible for allergic symptoms.

In addition to treating allergies, Medico IQ notes that Chlorpheniramine Maleate is sometimes used in combination with other medications for cold and flu relief. It is also included in some over-the-counter (OTC) decongestants and cough syrups to manage multiple symptoms.

How Chlorpheniramine Maleate Works

Chlorpheniramine Maleate is a first-generation antihistamine that inhibits the H1 histamine receptors. When an allergen enters the body, it triggers the immune system to release histamines, leading to inflammation and allergy symptoms. This medication counteracts these effects, reducing symptoms like nasal congestion, itching, and swelling.

Unlike newer antihistamines, Chlorpheniramine Maleate can cause drowsiness, as it crosses the blood-brain barrier and affects the central nervous system. This sedative effect is sometimes beneficial for patients experiencing severe allergic reactions or nighttime allergies.

Common Uses of Chlorpheniramine Maleate Tablet

This medication is used to treat various allergic conditions, including:

• Seasonal Allergies (Hay Fever): Helps relieve sneezing, nasal congestion, and itchy eyes caused by pollen.
• Perennial Allergic Rhinitis: Effective against year-round allergies caused by dust mites, mold, and pet dander.
• Common Cold Symptoms: Often included in cold and flu medications to alleviate runny nose and postnasal drip.
• Hives (Urticaria): Reduces itching, redness, and swelling associated with allergic skin reactions.
• Insect Bites & Stings: Helps control allergic reactions caused by insect bites.
• Drug or Food Allergies: Used in mild cases to prevent histamine-related symptoms.

Dosage and Administration

The correct dosage depends on the patient’s age, medical condition, and severity of symptoms. Below are the standard dosing guidelines:

• For Adults & Children (12 years and older): 4 mg every 4 to 6 hours as needed.
• Maximum daily dose: 24 mg per day.
• For Children (6 to 12 years): 2 mg every 4 to 6 hours as needed.
• Maximum daily dose: 12 mg per day.
• For Children (2 to 6 years): 1 mg every 4 to 6 hours as needed.
• Maximum daily dose: 6 mg per day.
• For Elderly Patients: A lower dose is recommended due to the increased risk of drowsiness, dizziness, and confusion.

It is crucial to follow the recommended dosage and avoid exceeding the daily limit to prevent side effects. Always consult a healthcare professional before administering this medication to children or elderly individuals.

Potential Side Effects

While Chlorpheniramine Maleate is generally safe, it may cause some side effects, including:

• Drowsiness or dizziness
• Dry mouth, nose, or throat
• Blurred vision
• Nausea or upset stomach
• Constipation

Less Common but Serious Side Effects:

• Difficulty urinating
• Increased heart rate (tachycardia)
• Confusion or hallucinations (in elderly patients)
• Allergic reactions (rash, swelling, or difficulty breathing)

If you experience any severe or unusual side effects, seek medical attention immediately.

Precautions & Warnings

Before taking Chlorpheniramine Maleate, consider the following precautions:

• Avoid Alcohol & Sedatives: This medication can enhance the sedative effects of alcohol, sleeping pills, and tranquilizers.
• Driving & Machinery: Due to its drowsiness-inducing effects, avoid driving or operating heavy machinery while taking this drug.
• Pregnancy & Breastfeeding: Consult a doctor before use, as the medication can pass into breast milk and may not be safe for pregnant women.
• Medical Conditions: If you have asthma, glaucoma, enlarged prostate, or high blood pressure, speak with your doctor before taking this medication.

Can You Take Chlorpheniramine Maleate with Other Medications?

Chlorpheniramine Maleate may interact with other drugs, such as:

• Other Antihistamines (Loratadine, Cetirizine): May cause excessive drowsiness.
• Decongestants (Pseudoephedrine): Often combined but should be used cautiously in patients with high blood pressure.
• Antidepressants (MAOIs & SSRIs): Can increase drowsiness and risk of side effects.
• Painkillers & Opioids: May lead to increased sedation and respiratory depression.

Always inform your doctor about any medications you are taking to prevent harmful drug interactions.

Conclusion

Chlorpheniramine Maleate Tablet is a reliable antihistamine used to relieve allergy symptoms, common colds, and other histamine-related conditions. While it is effective in managing sneezing, itching, and nasal congestion, it should be used responsibly due to its sedative effects.

Before taking this medication, ensure you follow the correct dosage, be mindful of potential side effects, and consult a doctor if you have underlying health conditions.

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