Hydroxychloroquine (HCQS 400 mg): Benefits, Dosage, Side Effects & How It Works

Written by Daniel Harris  »  Updated on: May 09th, 2025

Hydroxychloroquine (HCQS 400 mg): Uses, Dosage, Side Effects & Safety Guide

HCQS 400 mg is a powerful generic medication containing Hydroxychloroquine Sulfate, commonly used to treat malaria and chronic autoimmune diseases like rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Manufactured by IPCA Laboratories, this drug is trusted worldwide for its effectiveness and safety profile when used under medical supervision.


What is HCQS 400 mg?

HCQS 400 mg is an oral antimalarial and anti-inflammatory tablet that works by interfering with the function of immune system cells. Though originally developed to fight malaria, it has since gained importance in managing autoimmune diseases by reducing inflammation and immune overactivity.

This makes HCQS 400 a dual-action medication—effective against both parasitic infections and chronic inflammatory conditions.


Therapeutic Uses of HCQS 400 mg

1. Malaria Treatment & Prevention
  • Used to treat and prevent malaria caused by Plasmodium vivax, P. ovale, and other chloroquine-sensitive strains.
  • Not effective in regions with chloroquine-resistant malaria strains.
2. Rheumatoid Arthritis (RA)
  • Reduces joint pain, stiffness, and swelling by modulating immune response.
3. Systemic Lupus Erythematosus (SLE)
  • Manages lupus flares, skin symptoms, and systemic inflammation.
4. Other Off-Label Uses
  • Sometimes used in conditions like Sjogren's syndrome and cutaneous lupus based on physician discretion.


Dosage Guide

| Condition | Typical Adult Dose |

| -------------------- | ---------------------------------------------------------------------------------- |

| Malaria (Treatment) | 800 mg initially, then 400 mg after 6-8 hours, followed by 400 mg daily for 2 days |

| Malaria (Prevention) | 400 mg once weekly, starting 1-2 weeks before exposure |

| Rheumatoid Arthritis | 200–400 mg daily, depending on severity |

| Lupus | 200–400 mg daily as maintenance therapy |


How HCQS 400 mg Works

Hydroxychloroquine modifies how immune cells function and inhibits specific pathways involved in inflammation and autoimmunity. In malaria, it interferes with the parasite’s metabolism, preventing its replication inside red blood cells.

This mechanism of action makes HCQS 400 a vital medicine for both infectious and immune-mediated disorders.


Potential Side Effects

While HCQS 400 mg is generally well-tolerated, some patients may experience:

  • Nausea or vomiting
  • Abdominal pain or diarrhea
  • Skin rashes or itching
  • Headache or dizziness
  • Visual disturbances (especially with long-term use)
  • Retinal damage (rare, but serious with extended use)

💡 Regular eye check-ups are advised if using this medicine for more than 6 months.


Important Safety Information

  • Pregnancy & Breastfeeding: Use only if clearly needed and prescribed.
  • Liver & Kidney Conditions: Inform your doctor before starting.
  • Drug Interactions: Avoid combining with antacids, digoxin, or insulin without supervision.
  • Eye Health: Discontinue if you notice changes in vision or eye discomfort.


Why Buy HCQS 400 mg from GenericMedicine.Store?

At genericmedicine.store, we offer authentic HCQS 400 mg tablets shipped worldwide at competitive prices. Sourced from licensed manufacturers like IPCA, we ensure:

  • High-quality packaging
  • Reliable delivery outside India
  • Prescription support if needed
  • 100% customer confidentiality


Conclusion

HCQS 400 mg is a time-tested, multipurpose medication that helps manage serious health conditions when used correctly. Whether you're treating malaria or controlling autoimmune symptoms, HCQS can be a safe and effective option under medical guidance.












































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